II. Epidemiology

  1. Most common cause of Thrombocytopenia in pregnancy
  2. Incidence: 8% of pregnant women

III. Pathophysiology

  1. Increased Platelet clearance
  2. Hemodilution

V. Evaluation

  1. No additional evaluation required if
    1. Platelet Count >115,000 per uL and
    2. No signs of Preeclampsia or HELLP Syndrome
  2. Discuss lower Platelet Counts with hematology or maternal fetal medicine
  3. Obtain Platelet Count in newborns if maternal Immune Thrombocytopenic Purpura is suspected

VI. Differential Diagnosis

  1. See Thrombocytopenia
  2. Preeclampsia with HELLP Syndrome
  3. Immune Throbocytopenic Purpura

VII. Course

  1. Resolves spontaenously after delivery

VIII. Prognosis

  1. Benign condition with no associated increased morbidity or mortality in pregnant women or newborns

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