Pulmonary Hypertension in Sickle Cell Anemia

Aka: Pulmonary Hypertension in Sickle Cell Anemia, Sickle Cell Anemia Related Pulmonary Hypertension

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II. Epidemiology

  1. Prevalence: Up to 30% of Sickle Cell Anemia adults

III. Symptoms

  1. Dyspnea

IV. Signs

  1. Hypoxia
  2. Increased S2 Heart Sound

V. Imaging

  1. Chest XRay
    1. Right Ventricular Enlargement
  2. Echocardiogram
    1. Tricuspid regiurgitation

VI. Prognosis

  1. Increases mortality risk 10 fold

VII. References

  1. Gladwin (2004) N Engl J Med 350:886-95 [PubMed]

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