II. Indications
III. Preparation
- Consider Erythromycin 250 mg IV before endoscopy
- May allow better visualization if active bleeding
- Does not alter rate of identifying lesion
- Sears (1996) Gastrointest Endosc 43:A269 [PubMed]
IV. Techniques: Measures used to coagulate bleeding sites
- Indications: Active Upper Gastrointestinal Bleeding site
- Peptic Ulcer bleeding
- Arteriovenous Malformation
- Mallory-Weiss tear
- Dieulafoy Ulcer
- Efficacy
- All methods appear to be equally efficacious
- Many endoscopists both inject and coagulate lesions
- Thermal Contact
- Heater probe
- Multipolar electrocoagulation
- Surgical Clips
- Endoclips
- Bleeding site injection (typically combined with other measures)
- Epinephrine injection
- Alcohol injection (sclerosing agent)
- Higher risk of perforation
- Laser (rarely used)
- Nd:YAG Laser
- Argon Laser
V. Interpretation: Low Risk Findings
- Ulcer with clean base under 2 cm (5% rebleeding risk)
- Nonbleeding Mallory-Weiss Tear
- Esophagitis
- Gastritis
- Duodenitis
- Endoscopy negative for any lesion or fresh blood
- Failure to find source only adverse in over age 80
- Otherwise not related to adverse risk
VI. Interpretation: Moderate risk findings
- Ulcer with clean base over 2 cm in diameter
- Ulcer with clot or pigmented spot (10% risk of rebleed)
- Bleeding Mallory-Weiss tear with effective treatment
- Arteriovenous Malformation with successful treatment
- Portal gastropathy without Esophageal Varices
- Tumor identified on endoscopy
- Higher risk ulcer location
- Ulcer on lesser curvature of the Stomach
- Ulcer on posterior duodenal bulb
VII. Interpretation: High risk findings
- Actively bleeding ulcer or other bleeding lesion (12% Prevalence)
- Rebleeding rate without endoscopic treatment: 90%
- Rebleeding rate with successful endoscopic treatment: 15-30%
- Vessel visible on endoscopy (22% Prevalence)
- Rebleeding rate without endoscopic treatment: 50%
- Rebleeding rate with successful endoscopic treatment: 15-30%
- Adherent clot (10% Prevalence)
- Rebleeding rate without endoscopic treatment: 33%
- Rebleeding rate with successful endoscopic treatment: 5%
- Esophageal Varices with active bleeding
VIII. Management: Post-procedure
- Rebleeding occurs in 20% of cases despite treatment and requires repeat endoscopy
- Second-look endoscopy in 24 hours may be recommended
- Failed attempt to stop bleeding
- See Upper Gastrointestinal Bleeding
- Arteriography with embolization
- Surgery for severe ongoing bleeding