II. Pathophysiology

  1. Mechanisms: Joint degeneration with an increased risk of repeated Fracture and deformity
    1. Loss of proprioception
    2. Autonomic Dysfunction (vasomotor control loss)
  2. Typically affects weight bearing joints (knee, ankle and foot)

IV. Symptoms

  1. Relatively painless despite the severe deformity

V. Signs

  1. Loss of joint contour
  2. Great joint instability and Hypermobility

VI. Imaging

  1. Severe joint degeneration

VII. Complications

  1. Wound ulcers (high risk of Osteomyelitis)

VIII. References

  1. Augusta (2023) Crit Dec Emerg Med 37(1): 16-7

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Ontology: Neurogenic arthropathy (C0003892)

Definition (MSH) Chronic progressive degeneration of the stress-bearing portion of a joint, with bizarre hypertrophic changes at the periphery. It is probably a complication of a variety of neurologic disorders, particularly TABES DORSALIS, involving loss of sensation, which leads to relaxation of supporting structures and chronic instability of the joint. (Dorland, 27th ed)
Concepts Disease or Syndrome (T047)
MSH D001177
ICD9 713.5
ICD10 M14.6
SnomedCT 359554008, 77602000, 201734004, 239824003, 156514009, 268056006, 60730005, 67536000
English Neurogenic arthropathy, Arthropathies, Neurogenic, Arthropathy, Neurogenic, Charcot Joint, Charcot's Joint, Charcots Joint, Neurogenic Arthropathies, Joint, Charcot's, Neurogenic Arthropathy, NEUROGENIC OSTEOARTHROPATHY <CHARCOT JOINTS>, neuropathic joint disease (diagnosis), Charcot's arthropathy (diagnosis), neuropathic joint disease, Charcot's joint was observed, Arthropathy neurogenic, NEUROGENIC OSTEOARTHROPATHY CHARCOT JOINTS, Charcot's joint (physical finding), Arthropathy w nerve dis, Charcot arthropathy, Arthropathy, Neurogenic [Disease/Finding], charcot's joint, charcot's joint disease, arthropathy neurogenic, charcot arthropathy, neuropathic arthritis, arthropathy neuropathic, charcot joints, charcot's joints, charcots joint, neurogenic arthropathy, arthropathy charcots, charcot joint, neurogenic arthropathy charcot, charcot's arthropathy, charcots joints, neuropathic arthropathy, Charcôt's joint, Neuropathic arthropathy (& Charcot's) (disorder), Neuropathic arthropathy (& Charcot's), Neurogenic arthropathy of Charcot, Neurogenic arthropathy of Charcot (disorder), Charcot joints, Charcot's arthropathy, Charcot's joint, Arthropathy associated with a neurological disorder, Neuropathic arthropathy, Charcot's arthropathy (disorder), Arthropathy associated with a neurological disorder (disorder), Charcot's joint disease, Charcot's arthropathy (disorder) [Ambiguous], Neurogenic arthropathy of Charcot (disorder) [Ambiguous], Arthropathy associated with neurological disorders
Italian Artropatia neuropatica (di Charcot), Artropatia associata a disturbi neurologici, Artropatia di Charcot, Artropatia neurogena, Artropatia neuropatica di Charcot, Artropatie neuropatogene
Dutch Charcot-gewricht, Charcot-artropathie, artropathie geassocieerd met neurologische aandoeningen, neurogene artropathie, Neuropathische artropathie, neuropathische artropathie, Artropathie, neurogene, Charcot, ziekte van, Neurogene artropathie, Ziekte van Charcot
French Arthropathie neurogène, Articulation de Charcot, Arthropathie associée à des troubles neurologiques, Arthropathie neurogénique, Arthropathie neuropathique, Arthropathie nerveuse, Arthropathie de Charcot, Arthropathie tabétique, Neuro-arthropathie de Charcot, Neuroarthropathie de Charcot
German Charcot-Arthropathie, Arthropathie neurogen, Arthropathie assoziiert mit neurologischen Stoerungen, Neuropathische Arthropathie, Arthropathia neuropathica, Arthropathie, neurogene, Charcot-Gelenk
Portuguese Artropatia associada a afecções neurológicas, Artropatia neurogénica, Artropatia de Charcot, Artropatia neuropática, Articulação de Charcot, Artropatia Neurogênica
Spanish Artropatía de Charcot, Artropatía asociada a trastornos neurológicos, Artropatía neurógena, articulación de Charcot, artropatía neurogénica de Charcot (trastorno), enfermedad articular de Charcot, artropatía neurogénica de Charcot, artropatía neuropática, artropatía asociada con un trastorno neurológico (trastorno), artropatía asociada con un trastorno neurológico, artropatía de Charcot (concepto no activo), artropatía de Charcot (trastorno), artropatía de Charcot, artropatía neurogénica de Charcot (concepto no activo), Artropatía neuropática, Articulación de Charcot, Artropatía Neurogénica
Japanese シャルコー関節症, シャルコーカンセツショウ, シャルコーカンセツ, 神経因性関節障害, シンケイショウガイセイカンセツショウ, シンケイインセイカンセツショウガイ, Charcot関節, 関節障害-神経性, シャルコー関節, 神経原性関節症, 神経原性関節障害, 神経性関節症, 神経性関節障害, 神経障害性関節症, 神経障害性関節障害, 関節症-神経性, 関節障害-神経障害性
Swedish Ledsjukdom, neurogen
Finnish Neurogeeninen artropatia
Russian ARTROPATIIA NEVROGENNAIA, SHARKO SUSTAV, ARTROPATIIA NEIROGENNAIA, АРТРОПАТИЯ НЕВРОГЕННАЯ, АРТРОПАТИЯ НЕЙРОГЕННАЯ, ШАРКО СУСТАВ
Czech Artropatie spojená s neurologickými poruchami, Charcotova artropatie, Neuropatická artropatie, Neurogenní artropatie, neurogenní artropatie, artropatie neurogenní, Charcotův kloub
Korean 신경병증성 관절병증
Polish Stawy Charcota, Osteoartropatia neurogenna
Hungarian Neurologiai betegségekhez társult arthropathia, Charcot-ízület, Neuropathiás arthropathia, Neurogen arthropathia, Charcot arthropathia
Norwegian Nevrogen leddsykdom, Leddaffeksjon, nevrogen, Leddsykdom, nevrogen, Nevrogen leddaffeksjon, Charcots ledd