II. Epidemiology
- Renal Cysts are present in one third of older adults (Incidence increases with age)
III. Classification: Bosniak Classification
- Category I: Benign Simple Cyst- No monitoring needed
 
- Category II: Benign cystic lesion with some complex features- No monitoring needed
 
- Category IIF: Nonenhancing complex cysts >3 cm- Malignancy risk: 5-10%
- Follow with serial imaging
 
- Category III: Enhancing complex cysts- Malignancy risk: 50%
- Surgical resection
 
- Category IV: Malignant cystic mass- Surgical resection
 
IV. Evaluation
- Simple Renal Cysts- Benign in most cases
 
- Complex cysts- Complex cysts (especially with enhancement on imaging) have increased malignant potential
- Surgical resection for Category III and Category IV lesions
 
V. Labs: Biopsy indications
- Suspected abscess
- Suspected Lymphoma
- Suspected metastatic lesions
VI. Management
- Simple cysts (Category I and II) require no additional evaluation
- Fat containing solid lesions consistent with benign angiomyolipoma may be followed or biopsied
- Category IIF lesions should be followed
- Suspicious Renal Masses are resected surgically instead of biopsied (due to biopsy sampling error risk)
