II. Background
- Positive Pressure Ventilation (PPV) is single most important step in newborn CPR
III. Protocol
- Spontaneous Respirations
- No Respirations or gasping (secondary apnea) or Heart Rate <100/min
- Positive Pressure Ventilations (PPV) with Oxygen starting at 21% and titrating up
- Attach Oxygen Saturation to right hand (pre-ductal) within 1-2 minutes of starting PPV
- Avoid hyperoxygenation due to associated worse outcomes (titrate based on expected O2 Sat for minutes of life as listed below)
- Provide ventilations at rate of 40-60 per minute
- Count as "Breath - two - three"
- During CPR, Compressions to PPV ratio is 3:1
- Peak inspiratory pressure (PIP)
- Started at 20-25cm H2O
- Some infants may require 30-40 cm H2O
- Ventilate for 15-30 seconds before next assessment
- Continue PPV until Heart Rate >100/min and adequate spontaneous respirations
- Monitoring: Continuous Pulse Oximetry (targeted Pulse Oximetry values) from right hand (pre-ductal)
- At 1 minute of life: >60%
- At 2 minutes of life >65%
- At 3 minutes of life >70%
- At 4 minutes of life >75%
- At 5 minutes of life >80%
- At 10 minutes of life >85%
- Consider Orogastric Tube for prolonged PPV
- Perform Neonatal Circulation Assessment
- Positive Pressure Ventilations (PPV) with Oxygen starting at 21% and titrating up
IV. Management: Inadequate Positive Pressure Ventilation (no chest rise, no increase in Heart Rate)
- Adjust mask to obtain adequate seal
- Adjust head and neck position to reposition airway (sniffing position is ideal)
- Suction mouth and nose for secretions
- Open mouth slightly and move jaw forward
- Place index and middle finger inside mouth hooking behind central lower gums and gently lift upward
- Increase peak inspiratory pressure (PIP) enough to move chest (may require 30-40 cm H2O)
- May require blocking pop-off valve
- Consider intubation (see below)
- Consider RAM Nasal Cannula
- Allows for Positive Pressure Ventilation via Nasal Cannula (and mouth closed)
V. Management: Neonatal intubation
- Indications
- Tracheal Suctioning for thick meconium in a non-vigorous newborn
- Prolonged Positive Pressure Ventilations >2-3 minutes
- Ineffective Bag Valve Mask Ventilation
- Chest Compressions initiated
- Diaphragmatic Hernia suspected (or other Congenital Anomaly affecting intubation)
- Birth weight below 1500 grams (EGA under 30-31 weeks)
- Devices
- Mnemonics 0123 and 789 and 60
- Straight Blade 0 for a 1-2 kg newborn with an uncuffed 3-0 ET Tube
- ET Tube depth is 6+ wtKg (7 cm for 1 kg, 8 cm for 2 kg, 9 cm for 3 kg)
- Respiratory Rate 40-60 per minute
- Endotracheal Tube intubation
- Weight 1 kg: 2.5 mm Endotracheal Tube
- Weight 2 kg: 3.0 mm Endotracheal Tube
- Weight 3 kg: 3.5 mm Endotracheal Tube
- Laryngeal Mask Airway (LMA) size 1 (Gestational age >34 weeks or weight >2kg)
- Mnemonics 0123 and 789 and 60
- Confirmation
- Exhaled carbon dioxide detector or End-Tidal CO2 (etCO2) monitor changes from purple to yellow if in trachea
VI. References
- Bhalla (2014) Crit Dec Emerg Med 28(1): 2-11
- Kattwinkel (2000) Neonatal Resuscitation, AAP-AHA
- Kattwinkel (2010) Neonatal Resuscitation, AAP-AHA
- Raghuveer (2011) Am Fam Physician 83(8): 911-8 [PubMed]