Gouty Tophi

Aka: Gouty Tophi, Chonic Tophaceous Gout

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II. Pathophysiology

  1. Monosodium urate crystal deposits in soft tissue
  2. Occurs with >10 years of recurrent acute gout attacks

III. Symptoms

  1. Region
    1. Ear helix
    2. Olecranon process
    3. Overlying Interphalangeal joints
    4. Overlying Osteoarthritis-related Nodules (Heberden's Nodes, Bouchard's Nodes)

IV. Differential Diagnosis

  1. Rheumatoid Arthritis related Subcutaneous Nodules

V. Labs

  1. Nodule aspirate
    1. Monosodium urate crystals identified

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