II. Pathophysiology

  1. Retained alveolar fluid with incompletely expanded alveoli (typically due to precipitous Vaginal Delivery)
  2. Diagnosis of exclusion as a cause for Newborn Respiratory Distress
  3. Made in hindsight after no obvious other sources identified
    1. Tachypnea readily resolves within minutes to hours

III. Findings

  1. Respiratory Rate 60 to 80 breaths/min
  2. Mild increased work of breathing
  3. Improves rapidly after first 4 hours (contrast with TTN which typically lasts up to 48 hours)

IV. Differential Diagnosis

  1. See Respiratory Distress in the Newborn
  2. See Neonatal Distress Causes
  3. Transient Tachypnea of the Newborn (TTN)
    1. Respiratory Rate often >80 breaths/min
    2. Increased work of breathing
    3. Improves over 24-48 hours

V. Management

  1. Always consider the differential diagnosis
    1. Delayed transition (and TTN) are diagnoses of exclusion
  2. Supportive care
  3. Resolves spontaneously

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