II. Pathophysiology

  1. Immune-mediated erythematous rash

III. Signs

  1. Sun sensitive, erythematous rash
  2. Butterfly-shape appearance
  3. Involves both cheeks and variably the bridge of nose

IV. Differential Diagnosis: Miscellaneous

V. Differential Diagnosis: Infection

  1. Facial Erysipelas (Group A Streptococcal Cellulitis)
  2. Facial Staphylococcus aureusCellulitis
  3. Parvovirus B19 infection (slapped cheek appearance)
  4. Dental Abscess extension
  5. Wells’ syndrome (Eosinophilic Cellulitis)

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