II. Signs: Skin findings suggestive of infectious pathology
- Petechiae or Purpura (Systemic Vasculitis)
- Seborrheic rash (Histiocytosis X)
- Perineal rash (Kawasaki's Disease)
- Pallor, Jaundice or soft skin (Hyperthyroidism)
- Sparse eyebrows (anhydrotic ectodermal dysplasia)
- Hair Loss or breakage (Systemic Lupus Erythematosus)
- Characteristic rashes
- Tick-borne infection (e.g. Erythema Migrans in Lyme Disease)
- Herpes Simplex Virus
- Systemic Lupus Erythematosus (e.g. Malar Rash)
- Sarcoidosis (e.g. Lupus Pernio, Dactylitis, Erythema Nodosum)
- Still's Disease
- Faint salmon colored rash over trunk, palms and soles
-
Oral Ulcers
- Behcet Disease
- Systemic Lupus Erythematosus
III. Signs: Eye findings suggestive of infectious pathology
- Bulbar Conjunctivitis
- Palpebral or Bulbar injection
- Punctate Conjunctival Hemorrhages
- No pupillary constrictor response
- Familial Dysautonomia
- Fundus lesions
- Uveitis
IV. Signs: Hepatomegaly, Splenomegaly or abdominal mass
- Alcoholic Liver Disease or Cirrhosis
- Cancer (e.g. Hepatic Malignancy or Liver Metastases, Renal Mass)
- Cytomegalovirus
- Epstein-Barr Virus
- Leukemia
- Lymphoma
- Miliary Tuberculosis
- Q Fever (Hepatomegaly)
V. Signs: Musculoskeletal findings
- Joint Swelling or pain
- Bone findings suggestive of infectious pathology
- See Osteomyelitis
- See Vertebral Osteomyelitis
- Focal tenderness (assess for long bone Osteomyelitis)
VI. Signs: Lymph Node findings suggestive of infectious pathology
- Generalized Lymphadenopathy
- Localized or nontender adenopathy
- Malignancy
VII. Signs: Cardiac findings suggestive of infectious pathology
- Diastolic insufficiency murmurs
- Widened Pulse Pressure
