II. Pathophysiology

  1. Typically develop from Vesicles or bullae that fill with pus, or from Hair Follicles or Sweat Glands
    1. May also spontaneous form a non-follicular Pustule

III. Description

  1. Raised, translucent superficial, circumscribed skin lesion
  2. Contains purulent exudate (white, orange, yellow, green)
  3. Follicular Pustules are conical with hair in center
    1. Non-follicular Pustules vary in shape

IV. Differential Diagnosis: Hemorrhagic Pustules (or Necrotic Pustules)

V. Labs

  1. Gram Stain and culture of pustular discharge (exclude disseminated Gonorrhea)

VI. Examples

  1. Drug eruption
  2. Acne Vulgaris
  3. Generalized Pustular Psoriasis syndrome
  4. Viral vessicular eruptions may develop into Pustules (e.g. varicella, Herpes Zoster virus, Herpes Simplex Virus)

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Ontology: pustule (C0241157)

Definition (SCTSPA) Vesícula llena de leucocitos
Definition (SNOMEDCT_US) A vesicle filled with leukocytes
Concepts Finding (T033)
SnomedCT 271760008, 47002008
English Skin Pustule(s), skin pustules, skin pustules (physical finding), pustules, pustules were seen, skin pustule, pimple, Pustule of skin, Skin pustule, Cutaneous pustule, Pustule, Pussey spot, Pustule (disorder), Pustule (morphologic abnormality), Pustule, NOS, pustule
Dutch pustula
French Pustule
German Pustel
Italian Pustola
Portuguese Pústula
Spanish Pústula, pústula (anomalía morfológica), pústula (trastorno), pústula
Japanese 膿疱, ノウホウ
Czech Pustula
Hungarian pustula