Endometritis

Aka: Endometritis, Endomyometritis

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II. Causes

  1. Pelvic Inflammatory Disease
  2. Postpartum
    1. Chorioamnionitis
    2. Endometritis
      1. Early Postpartum (<48 hours) after C-Section
      2. Late Postpartum (48 hours - 6 weeks) after NSVD
  3. Uterine instrumentation
  4. Septic Abortion

III. Pathophysiology

  1. Bacterial Infection of the Uterus
    1. Bacteroides
    2. Group B Streptococcus
    3. Group A Streptococcus
    4. Enterobacteriaceae
    5. Chlamydia Trachomatis
    6. M. hominis

IV. Symptoms

  1. Lower abdominal cramps
  2. Foul Vaginal Discharge
  3. Nausea and Vomiting

V. Signs

  1. Fever
  2. Lower abdominal tenderness and Muscle spasm
  3. Cervical motion tenderness

VI. Labs

  1. Complete Blood Count
    1. Leukocytosis
  2. Gram Stain and culture of cervical discharge
  3. Gonorrhea Culture
  4. Chlamydia swab

VII. Management

  1. See Endometritis Management
  2. Inpatient (Indicated in most cases)
    1. Option 1
      1. Cefoxitin OR Timentin OR Imipenem OR Unasyn AND
      2. Doxycycline
    2. Option 2
      1. Clindamycin AND
      2. Ceftriaxone OR Cefotaxime OR Gentamycin
  3. Outpatient (Indicated for late Postpartum Endometritis)
    1. Non-lactating mother
      1. Doxycycline 100 mg q12h IV or PO for 14 days
    2. Lactating mother
      1. Doxycycline
        1. Pump and dispose of milk
      2. Clindamycin may be effective

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Related Studies

Ontology: Endometritis (C0014179)

Definition (NCI_CTCAE) A disorder characterized by an infectious process involving the endometrium. It may extend to the myometrium and parametrial tissues.
Definition (NCI) An acute or chronic, usually bacterial infectious process affecting the endometrium. It may extend to the myometrium and parametrial tissues. Symptoms include lower abdominal pain, vaginal discharge, and vaginal bleeding.
Definition (MSH) Inflammation of the ENDOMETRIUM, usually caused by intrauterine infections. Endometritis is the most common cause of postpartum fever.
Concepts Disease or Syndrome (T047)
MSH D004716
SnomedCT 198192000, 266653006, 155975003, 266652001, 78623009
French ENDOMETRITE, Endométrite SAI, Endométrite
English ENDOMETRITIS, Endometritis unspecified, Endometritis, endometritis, endometritis (diagnosis), Endometritis NOS, Uterine Infection, Endometritis [Disease/Finding], Endometritis unspecified (disorder), Uterine infection, Endometritis (disorder), Endometritis, NOS
Portuguese ENDOMETRITE, Endometrite NE, Endometrite
Spanish ENDOMETRITIS, Endometritis NEOM, endometritis, no especificada, endometritis, no especificada (trastorno), endometritis (trastorno), endometritis, Endometritis
German ENDOMETRITIS, Endometritis NNB, Endometritis
Dutch endometritis NAO, endometritis, Endometritis
Italian Endometrite NAS, Endometrite
Japanese 子宮内膜炎, 子宮内膜炎ＮＯＳ, ｼｷｭｳﾅｲﾏｸｴﾝ, ｼｷｭｳﾅｲﾏｸｴﾝNOS
Swedish Livmoderslemhinneinflammation
Czech sliznice děložní - zánět, endometritida, Endometritida, Endometritida NOS
Finnish Endometriitti
Russian ENDOMETRIT, ЭНДОМЕТРИТ
Croatian ENDOMETRITIS
Polish Zapalenie błony śluzowej macicy
Hungarian Endometritis k.m.n., Endometritis
Norwegian Endometritt, Livmorslimhinnebetennelse, Betennelse i livmorslimhinnen
Derived from the NIH UMLS (Unified Medical Language System)

Ontology: Endomyometritis (C0269050)

Definition (MSH) Inflammation of both the ENDOMETRIUM and the MYOMETRIUM, usually caused by infections after a CESAREAN SECTION.
Concepts Disease or Syndrome (T047)
MSH D004716
SnomedCT 198193005, 88027004
English Endomyometritis unspecified, Endomyometritis, endomyometritis, endomyometritis (diagnosis), Endomyometritis unspecified (disorder), Endomyometritis (disorder), Endomyometritis, NOS
Dutch endomyometritis
Spanish Endrometritis, Endomiometritis, endomiometritis, no especificada (trastorno), endomiometritis, no especificada, endomiometritis (trastorno), endomiometritis
Japanese 子宮内膜筋層炎, ｼｷｭｳﾅｲﾏｸｷﾝｿｳｴﾝ
Czech endomyometritida, Endomyometritida
Portuguese Endomiometrite
French Endomyométrite
German Endomyometritis
Hungarian Endomyometritis
Norwegian Endomyometritt
Italian Endomiometrite
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Infectious Disease

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