II. Background

  1. Water soluble B Vitamin
  2. Wide variety of food sources
  3. Deficiency (rare)
    1. Fatigue
    2. Nausea or Vomiting
    3. Abdominal Pain

III. Physiology

  1. Antioxidant properties
  2. Part of Coenzyme A (Acetyl CoA, succinyl CoA, malonyl CoA), and of B2 complex
  3. Part of acyl carrier Protein in Fatty Acid synthesis
  4. Growth factor
  5. Carbohydrate, Protein and Fat Metabolism
  6. Lipid, Cholesterol and steroid Hormone synthesis

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Ontology: Pantothenic Acid (C0030342)

Definition (NCI) A water-soluble vitamin ubiquitously found in plants and animal tissues with antioxidant property. Vitamin B5 is a component of coenzyme A (CoA) and a part of the vitamin B2 complex. Vitamin B5 is a growth factor and is essential for various metabolic functions, including the metabolism of carbohydrates, proteins, and fatty acids. This vitamin is also involved in the synthesis of cholesterol, lipids, neurotransmitters, steroid hormones, and hemoglobin.
Definition (NCI_NCI-GLOSS) A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Pantothenic acid helps some enzymes use foods and make many substances used in the body and protects cells against damage from peroxides. It is found in almost all plant and animal foods. Pantothenic acid is water-soluble (can dissolve in water) and must be taken in every day.
Definition (NCI_CRCH) Water-soluble vitamin that is a component of coenzyme A and phosphopantetheine, which are involved in fatty acid metabolism. (DRI)
Definition (MSH) A butyryl-beta-alanine that can also be viewed as pantoic acid complexed with BETA ALANINE. It is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE.
Concepts Vitamin (T127) , Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D010205
SnomedCT 86431009, 66441000
English Pantothenic Acid, beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, (R)-, beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,(R)-(9CI), D-Pantothenic Acid, VITAMIN B A 05, pantothenic acid (medication), vitamins pantothenic acid, vitamin B5, N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine, beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, Pantothenic Acid [Chemical/Ingredient], PANTOTHENIC ACID, b5 vitamins, vitamin b5, acid pantothenic, b5 vitamin, pantothenic acid, Vitamin B<sub>5</sub>, Vitamin B>5<, Pantothenic acid, Pantothenic acid preparation, Pantothenic acid (substance), Pantothenic acid preparation (product), Pantothenic acid preparation (substance), B 5, Vitamin, B5, Vitamin, Vitamin B 5, Vitamin B5, VITAMIN B5
Swedish Pantotensyra
Finnish Pantoteenihappo
Japanese パントテン酸カルシウム, D(+)-パントテン酸, パントテン酸, パンカル
Spanish preparado con ácido pantoténico (producto), ácido pantoténico (producto), preparado con ácido pantoténico, Vitamina B5, vitamina B5, preparado de ácido pantoténico (sustancia), ácido pantoténico (sustancia), ácido pantoténico, Ácido Pantoténico, Vitamina B 5
Czech kyselina pantothenová, kyselina pantotenová
Polish Kwas pantotenowy
Portuguese Vitamina B5, Ácido Pantotênico, Vitamina B 5
French Acide pantothénique, Vitamine B5
German Pantothensäure
Italian Acido pantotenico