II. Evaluation
- Migraine Treatment Optimization Questionnaire 4 (mTOQ-4)
III. Management: Office-Based Acute Migraine Management (adult dosing)
- See Acute Migraine Headache Medication
- See Migraine Headache Care in the Emergency Department
-
Oral Analgesics (combined with other agents below)
- Acetaminophen
- NSAID (Ibuprofen orally or Ketorolac IV or IM)
-
Antiemetics with Migraine-specific activity
- Metoclopramide 10 mg IM or very slowly IV, or oral
- Prochlorperazine IM or IV, or oral
- Acute Triptans (if not contraindicated, and early presentations)
- Sumatriptan SQ or Intranasal
- Rizatriptan MLT
-
CGRP Antagonist
- Zavegepant (Zavzpret) nasal spray
- Consider adjunctive agents
- Dexamethason 10 mg oral, IM or IV
- Consider Nerve Block in Occipital Headache
- Greater Occipital Nerve Block
- May be combined with Supraorbital Nerve Block
- Greater Occipital Nerve Block
- References
- (2026) Presc Lett 33(4): 7-8
IV. Management: Clinic Routine Follow-Up Schedule
- Visit 1 - Initial Evaluation
- Primary Goal
- Rule-out Organic Headache (Secondary Headache)
- Secondary Goals
- Eliminate Rebound Migraine habits (e.g. Analgesic use >10 days/month)
- Avoid Migraine Headache Triggers
- Patient Education Handouts regarding Headache
- Primary Goal
- Visit 2 - See 2-4 weeks after initial visit
- Primary Goal
- Establish Migraine Abortive Management
- Secondary Goals
- Review Migraine Headache Pathophysiology
- Review Headache Self-Help Measure
- Primary Goal
- Visit 3+ - See every 1-3 months until stable
- Primary Goal
- Consider Migraine Prophylaxis
- Secondary Goal
- Adjust Migraine Abortive Management
- Primary Goal
- Visit 4+ - See 2-4 times per year
- Primary Goal
- Turn Migraine Headache control over to patient
- Review Headache Self-Help Measure
- Secondary Goals
- Adjust Migraine Abortive Management
- Adjust Migraine Prophylaxis
- Primary Goal