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Ontology:
Janus kinase
(C0597721)
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Definition (CSP)
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nonEC; family of cytoplasmic protein tyrosine kinases.
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|
Definition (MSH)
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A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.
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| Concepts |
Amino Acid, Peptide, or Protein
(T116)
, Enzyme
(T126)
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| MSH |
D053612
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| English |
JAK Kinases, Janus Kinases, Kinases, JAK, Kinases, Janus, JAK kinase, Janus kinase, Janus Kinases [Chemical/Ingredient] |
| Portuguese |
Janus Quinases, Janus-Quinases, Quinases Janus |
| Spanish |
Quinasas Janus, Janus-Cinasas, Janus Quinasas, Cinasas Janus, Janus Cinasas, Janus-Quinasas |
| Russian |
JANUS-КИНАЗЫ, ЯНУС-КИНАЗЫ, JANUS-KINAZY, IANUS-KINAZY |
| Italian |
Chinasi Giano, Jak chinasi |
| German |
JAK-Kinasen, Janus-Kinasen |
| French |
Janus kinases, Tyrosine-kinases JAK, Tyrosine kinases JAK, JAK Kinases, Kinases JAK, Protéines tyrosine kinases JAK |
| Finnish |
Janus-kinaasit
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| Czech |
kinasy JAK, Janus kinasy, JAK kinasy |
| Japanese |
ヤヌスキナーゼ
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| Swedish |
Januskinaser
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| Polish |
Kinazy JAK
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| Croatian |
JANUS KINAZE, JAK |
