II. Pathophysiology
- Cross-over syndrome of Polymyositis or Dermatomyositis with other Connective Tissue Disorders
III. Signs
- Fever
- Nonerosive Arthritis
- Raynaud Phenomenon
- Interstitial Lung Disease
- Distal Fingertip fissures (mechanic's hands)
IV. Labs
- See Polymyositis and Dermatomyositis
- Screening
- Confirmation
- Myositis specific antibodies (of which Anti-Jo-1 Antibody is most sensitive) are only positive in 20% of cases