II. Causes: Chronic Cough in Infancy

  1. Congenital Anomaly
    1. Airway malformation
    2. Tracheoesophageal fistula
    3. Vascular Ring
    4. Primary ciliary Dyskinesia
    5. Cystic Fibrosis
    6. Immune deficiency
  2. Infection
    1. Respiratory Syncytial Virus (RSV)
    2. Cytomegalovirus (CMV)
    3. Pertussis
    4. Chlamydia
    5. Tuberculosis

III. Causes: Chronic Cough in preschool children

  1. Reactive changes
    1. Asthma
    2. Postnasal discharge (Sinusitis)
  2. Passive smoke
  3. Infection
    1. Viral causes
    2. Pertussis
    3. Mycoplasma pneumonia
    4. Tuberculosis
  4. Foreign Body Aspiration
  5. Congenital Anomaly
    1. Cystic Fibrosis
    2. Primary ciliary Dyskinesia
    3. Immune deficiency

IV. Causes: Chronic Cough in school age children (ages 6 to 15 years old)

  1. Reactive changes
    1. Asthma
    2. Environmental irritants (e.g. Air Pollution, Active or passive smoking)
    3. Upper Airway Cough Syndrome (Post Nasal Discharge)
  2. Gastroesophageal Reflux
  3. Protracted Bacterial Bronchitis
    1. Di Filippo (2018) Ann Thoracic Med 13(1): 7-13 [PubMed]
  4. Lung Infection
    1. Mycoplasma pneumonia
    2. Tuberculosis
  5. Other uncommon causes
    1. Immunodeficiency
    2. Cystic Fibrosis
    3. Psychogenic cough
    4. Tourette syndrome
    5. Bronchiectasis
    6. Aspiration lung disease

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