Otolaryngology Book

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Nasal Disease

  • Loss of Smell

Salivary Gland Disorders

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Vestibular Disorders

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Loss of SmellAka: Smell Dysfunction, Anosmia, Hyposmia

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  1. Testing
    1. Confirm that nares are patent prior to testing
    2. Patient closes eyes and occludes one nare
      1. Test for recognition of common substances
      2. Examples: Cloves, coffee, soap, vanilla
  2. Causes: Loss of smell due to local nasal causes
    1. Allergic Rhinitis
    2. Upper Respiratory Infection
    3. Nasal Polyposis
    4. Sinusitis
  3. Causes: Loss of smell due to Systemic Conditions
    1. Renal Failure
    2. Hepatic failure
    3. Vitamin B12 Deficiency
    4. Cushing's Syndrome
    5. Hypothyroidism
    6. Diabetes Mellitus
    7. Viral Hepatitis
    8. Influenza
    9. Kallmann's Syndrome
    10. Drugs
      1. Tobacco smoke
      2. Alcohol
      3. Amphetamines
      4. Topical Cocaine
    11. Medications
      1. Nasal Sprays
      2. Antibiotics (Aminoglycosides, Tetracycline)
    12. Heavy metals (e.g. Lead, Mercury)
  4. Causes: Loss of smell due to Neurologic
    1. Head Trauma
    2. Multiple Sclerosis
    3. Parkinson's Disease
    4. Frontal tumor
    5. Alzheimer's Disease
    6. Korsakoff's Psychosis
  5. References
    1. Baloh in Goldman (2000) Cecil Medicine, p. 2249-50
    2. Snow in Wilson (1991) Harrison's Internal Med, p. 152

Anosmia (C0003126)

Definition (CSP)absence of the sense of smell.
Definition (MSH)Absence of the sense of smell. (Dorland, 27th ed)
ConceptsSign or Symptom (T184)
ICD9781.1
MSHD000857
EnglishAbsent sense of smell, Absent smell, Anosmia, Anosmia - loss of smell sense, anosphrasia, Loss of sense of smell, Loss of the sense of smell, No sense of smell, Sense of smell absent, Sense of smell lost, SMELL LOSS
Spanishanosmia, ausencia del sentido del olfato, olfato ausente, perdida del sentido del olfato
Parent ConceptsDisorder of olfactory system (C0679441), [D]Smell and taste disorder (C0495689), Finding of sense of smell (C0576646), Nose finding (C1269534), Duplicate concept (C1274013)
SourcesAOD, COSTAR, CSP, CST, DXP, MEDLINEPLUS, MSH, MTH, MTHICD9, OMIM, QMR, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Sense of smell impaired (C0234260)

ConceptsFinding (T033)
EnglishDecreased sense of smell, Defect or impairment of sense of smell, Difficulty in distinguishing different smells, Hyposmia, OLFACTORY IMPAIRMENT, Reduced sense of smell, Sense of smell impaired
Spanishalteracion en el sentido del olfato, disminucion del sentido del olfato
Parent ConceptsFinding of sense of smell (C0576646), Nose finding (C1269534)
SourcesCSP, DXP, OMIM, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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