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FlecainideAka: Tambocor
- Indications: Atrial Fibrillation Cardioversion
- Time to Cardioversion: 3-8 hours
- Conversion Rate: 68-91%
- Chronic Efficacy: 40-74%
- Dose
- Load: 300-400 mg PO single bolus dose
- Maintenance: 50-150 mg PO bid
Flecainide (C0016229) | |
|---|---|
| Definition (MSH) | A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial arrhythmias and tachycardias. Paradoxically, however, in myocardial infarct patients with either symptomatic or asymptomatic arrhythmia, flecainide exacerbates the arrhythmia and is not recommended for use in these patients. |
| Definition (NCI) | A synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system. It also decreases phase 4 slope and increases the depolarization threshold. (NCI04) |
| Definition (NCI) | A drug that is used to treat abnormal heart rhythms. It may also relieve neuropathic pain, the burning, stabbing, or stinging pain that may arise from damage to nerves caused by some types of cancer or cancer treatment. |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D005424 |
| English | Flecainide, FLECAINIDE PREPARATION |
| Spanish | flecainida |
| Parent Concepts | Piperidines (C0031960), Anti-Arrhythmia Agents (C0003195), Class Ic antiarrhythmic drug (C0304505), Antiarrhythmics - Classes IA, B, and C (C1579436) |
| Sources | LNC, MSH, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF Derived from the NIH UMLS (Unified Medical Language System) |
Tambocor (C0592158) | |
|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D005424 |
| English | 3M Brand of Flecainide Acetate, Apocard, Riker Brand of Flecainide Acetate, Tambocor, United Drug Brand of Flecainide Acetate |
| Sources | MSH, RXNORM Derived from the NIH UMLS (Unified Medical Language System) |
