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Antiarrhythmic

Aka: Antiarrhythmic, Vaughn Williams Classification
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  1. Class I: Sodium Channel Blockade
    1. Class Ia: Lengthens action potential duration
      1. Quinidine
      2. Procainamide (Pronestyl)
      3. Disopyramide (Norpace)
      4. Imipramine (MAO inhibitor)
      5. Amiodarone (also Class II, III, IV)
    2. Class Ib: No effect on action potential
      1. Lidocaine (Xylocaine)
      2. Tocainide (Tonocard)
      3. Mexiletine (Mexitil)
      4. Phenytoin (Dilantin)
    3. Class Ic: Greater sodium current depression
      1. Flecainide (Tambocor)
      2. Encainide (Enkaid)
      3. Propafenone
  2. Class II: Beta Blocker
    1. Esmolol (Brevibloc)
    2. Sotalol (also Class III)
    3. Amiodarone (also Class Ia, III, IV)
  3. Class III: Prolong Refractory period via action potential
    1. Bretylium (Bretylol)
    2. Sotalol
    3. Amiodarone (also Class Ia, II, IV)
  4. Class IV: Calcium Channel Blocker
    1. Verapamil (Calan)
    2. Diltiazem (Cardizem)
    3. Amiodarone (also Class Ia, II, III)

Anti-Arrhythmia Agents (C0003195)

Definition (NCI) Agents used for the treatment or prevention of cardiac arrhythmias; they may effect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. (CRISP)
Definition (MSH) Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Definition (CSP) group of agents used for the treatment or prevention of cardiac arrhythmias; they may effect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers.
Concepts Pharmacologic Substance (T121)
MSH D000889
SnomedCT 67507000, 372813008
English Agents, Anti-Arrhythmia, Anti Arrhythmia Agents, antiarrhythmic agent, Agents, Antiarrhythmia, Anti Arrhythmia Drugs, Anti Arrhythmics, Anti-Arrhythmia Drugs, Anti-Arrhythmics, Antiarrhythmia Agents, Antiarrhythmia Drugs, Antiarrhythmic Drugs, Drugs, Anti-Arrhythmia, Drugs, Antiarrhythmia, Drugs, Antiarrhythmic, ANTIARRHYTHMIC DRUGS, Antiarrhythmic drug, NOS, Antiarrhythmic Agent, ANTIARRHYTHMIA AGENTS, ANTIARRHYTHMICS, antiarrhythmic agents (medication), anti-arrhythimia agents, antiarrhythmia agents, antiarrhythmic agents, 801 ANTIARRHYTHMIC DRUGS, Cardiac Depressant, Anti-arrhythmic Agent, Anti-arrhythmic, Antiarrhythmic, [CV300] ANTIARRHYTHMICS, Anti-arrhythmic Agent [TC], Antiarrhythmic [EPC], agents antiarrhythmic, antiarrhythmia drugs, antiarrhythmic drugs, anti arrhythmia drugs, anti arrhythmic, antiarrhythmic, anti arrhythmics, anti-arrhythmia drugs, anti-arrhythmics, antiarrhythmic drug, antiarrhythmics, Anti-Arrhythmia Agents, Antiarrhythmic drug, Antiarrhythmic agent (substance), Antiarrhythmic agent, Antiarrhythmic drug (product), Antiarrhythmic drug (substance), antiarrhythmia, Antiarrhythmics
French Médicaments antiarythmiques, Anti-arythmiques, Agents antiarythmiques, Antiarythmisants, Antiarythmiques
Swedish Antiarytmika
Czech antiarytmika
Finnish Rytmihäiriölääkkeet
Italian Farmaci antiaritmia, Farmaci antiaritmici, Antiaritmici
Russian PROTIVOARITMICHESKIE SREDSTVA, MIOKARDIAL'NYE DEPRESSANTY, KARDIAL'NYE DEPRESSANTY, ANTIARITMICHESKIE SREDSTVA, ANTIFIBRILLIATORNYE SREDSTVA, АНТИАРИТМИЧЕСКИЕ СРЕДСТВА, АНТИФИБРИЛЛЯТОРНЫЕ СРЕДСТВА, КАРДИАЛЬНЫЕ ДЕПРЕССАНТЫ, МИОКАРДИАЛЬНЫЕ ДЕПРЕССАНТЫ, ПРОТИВОАРИТМИЧЕСКИЕ СРЕДСТВА
Japanese 抗不整脈薬, 不整脈治療薬, 心筋抑制薬, 心抑制薬, 抗不整脈剤, 抗心臓細動薬
Croatian ANTIARITMIJSKI LIJEKOVI
Polish Leki przeciwarytmiczne, Leki umiarawiające, Depresanty mięśnia sercowego, Leki antyarytmiczne
Spanish agente antiarrítmico (sustancia), agente antiarrítmico, antiarrítmicos, antiarrítmico, droga antiarrítmica (producto), droga antiarrítmica (sustancia), droga antiarrítmica, fármaco antiarrítmico (producto), fármaco antiarrítmico, Agentes Antiarritmicos, Agentes Antiarrítmicos
German Antiarrhythmika
Portuguese Antiarrítmicos
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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