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PropranololAka: Inderal

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  1. Mechanism
    1. Non-Selective Beta Blocker
  2. Indications
    1. Hypertension
    2. Atrial Fibrillation Rate Control
    3. Hyperthyroidism
    4. Performance Anxiety
  3. Dosing: Oral
    1. Regular: 40 mg PO bid (MAX: 640 mg/day)
    2. Extended: 80 mg PO qd (MAX: 320 mg/day)
  4. Dosing: Intravenous
    1. Load: 1-3 mg IV over 2-5 minutes
    2. Repeat every 2 minutes to a total dose of 0.1 mg/kg
    3. Sustained response for 6-8 hours

Propranolol (C0033497)

Definition (MSH)A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
Definition (CSP)noncardioselective beta adrenergic antagonist; used in treatment or prevention of many disorders including acute myocardial infarction, arrhythmias, angina pectoris, hypertension, hyperthyroidism, migraine; pheochromocytoma, etc.
Definition (NCI)A synthetic, nonselective beta-adrenergic receptor blocker with antianginal, antiarrhythmic, antihypertensive properties. Propranolol competitively antagonizes beta-adrenergic receptors, thereby causing negative chronotropic and inotropic effects leading to a reduction in cardiac output.
ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHD011433
EnglishPropanolol, Propranolol, PROPRANOLOL PREPARATION
Spanishpropranolol
Parent ConceptsPropanolamines (C0033442), Anti-Arrhythmia Agents (C0003195), beta antiadrenergic agent (C0178504), Naphthylamines (C0260030), Coronary vasodilator (C0596385), Naphthalenes (C0027378), Phenoxypropanolamines (C1563753), Adrenergic beta-Antagonists (C0001645), [CV100] BETA-BLOCKERS/RELATED (C0973513), Non-selective beta-blocking agent (C0304515), Class II antiarrhythmic drug (C0360701)
SourcesAOD, CSP, LNC, MSH, MTH, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF
Derived from the NIH UMLS (Unified Medical Language System)


Inderal (C0591636)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHD011433
EnglishInderal
SourcesCSP, MSH, NCI, RXNORM
Derived from the NIH UMLS (Unified Medical Language System)



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