Togaviridae

Aka: Togaviridae, Togavirus, Togaviridae Infection, Togavirus Infection, Alphavirus, Alphaviridae, Alphavirus Infection

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II. Pathophysiology

  1. Family Togaviridae (Togavirus) are primarily aboviruses (arthropod borne) found in the genus Alphavirus
    1. Togaviridae also includes Genus Rubivirus (including Rubella) which are not Arboviruses
  2. Togaviridae are enveloped, Icosahedral, single stranded RNA Viruses
  3. Togaviridae are Message Sense RNA Viruses (Positive Stranded, +ssRNA)
    1. Message sense RNA (+ssRNA) are identical to Messenger RNA (mRNA)
    2. Like mRNA, +ssRNA may be immediately translated by host ribosomes into Protein

III. Types

  1. Genus Alphavirus (Mosquito-borne)
    1. Alpha viruses manifesting with Encephalitis
      1. Eastern Equine Encephalitis virus
      2. Venezuelan equine Encephalitis virus
      3. Western equine Encephalitis virus
    2. Alpha viruses with other manifestations
      1. Ross River virus (epidemic Polyarthritis)
      2. Chikungunya
  2. Genus Rubivirus
    1. Rubella (not an Arbovirus)

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