II. Definitions
- Organ failure
- Shock or
- Hypoxemia (paO2 60 mmHg or less)
- Serum Creatinine >2 mg/dl
- Gastrointestinal Bleeding >500 ml/24 hours
- Local complications
- Pancreatic necrosis
- Pancreatic Abscess
- Pseudocyst
- Early prognostic signs (systemic complications)
- Ranson score 3 or greater
- APACHE II Score 8 or greater
III. Severity: Mild Acute Pancreatitis
- No organ failure
- No local complications (e.g. peri-pancreatic fluid collection, pancreatic necrosis)
- No systemic complications
IV. Severity: Moderate Acute Pancreatitis
- Transient organ failure (<48 hours) or
- Local complications or
- Exacerbation of comorbidity
V. Severity: Severe Acute Pancreatitis
- Persistent organ failure (>48 hours)
VI. Interpretation
- Mild Acute Pancreatitis
- Mortality <1%
- Resolves within 1 week in most cases
- Severe Acute Pancreatitis
- Mortality approaches 30%