II. Indications

  1. Pulmonary Function Test Interpretation (Used in ATS Guidelines)

III. Background

  1. Based on Third National Health and Nutrition Examination Survey (NHANES III) PFT data
  2. Calculated the lowest 5% (fifth percentile) cut-offs for FEV1 to FVC, FVC and FEV1
  3. Replaces GOLD Criteria which are less accurate
    1. Miss up to 50% of young adults with Obstructive Lung Disease and
    2. Overdiagnose Obstructive Lung Disease in healthy non-smokers
  4. Recently manufactured PFT software calculates the LLN based on patient age, gender and height

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