Purpura fulminans

Aka: Purpura fulminans

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II. Pathophysiology

  1. Associated with Disseminated Intravascular Coagulopathy
  2. Possible etiologies
    1. Severe Bacterial Infection (Meningococcemia)
    2. Protein C Deficiency
    3. Protein S Deficiency

III. Signs

  1. See also Disseminated Intravascular Coagulopathy
  2. Minimal inflammation
  3. Rapidly progressive Purpura
    1. Microvascular thrombosis in Dermis
    2. Perivascular Hemorrhage
    3. Necrotic gangrene

IV. Prognosis

  1. Frequently lethal condition

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