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Dipyridamole
Aka: Dipyridamole, Persantine, Aggrenox- Indications
- Cerebrovascular Accident Prevention
- Alternative for Aspirin sensitive patient
- Use Dipyridamole alone (Aggrenox contains Aspirin)
- Mechanism
- Inhibits platelet aggregation
- Dipyridamole acts at platelet phosphodiesterase
- Dosing
- Dipyridamole (Persantine)
- Dose: 75 mg PO qid
- Aggrenox (Dipyridamole 200 mg and Aspirin 25 mg)
- Dose: 1 capsule bid
- Dipyridamole (Persantine)
| Medication Costs | ||
|---|---|---|
| Dipyridamole (on 2/9/2012 at DrugStore.com) | ||
| Dipyridamole 25mg Tablets | #100 for $35.99 | ($0.36/unit) |
| Dipyridamole 50mg Tablets | #90 for $57.99 | ($0.64/unit) |
| Dipyridamole 75mg Tablets | #100 for $81.99 | ($0.82/unit) |
| Persantine (on 2/9/2012 at DrugStore.com) | ||
| Persantine 25mg Tablets | #100 for $85.99 | ($0.86/unit) |
| Persantine 50mg Tablets | #100 for $139.99 | ($1.40/unit) |
| Persantine 75mg Tablets | #100 for $169.99 | ($1.70/unit) |
| Aggrenox (on 2/9/2012 at DrugStore.com) | ||
| Aggrenox 25-200mg 12 Hour Capsule | #60 for $242.99 | ($4.05/unit) |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
Dipyridamole (C0012582) |
|
|---|---|
| Definition (MSH) | A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752) |
| Definition (NCI) | A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. (NCI04) |
| Definition (CSP) | platelet inhibitor and coronary vasodilator used to prevent thromboembolism associated with mechanical heart valves, as prophylactic adjunct in the prevention of myocardial reinfarction, and as a diagnostic aid adjunct in myocardial perfusion imaging; administered orally and intravenously. |
| Definition (NCI) | A drug that prevents blood cell clumping and enhances the effectiveness of fluorouracil and other chemotherapeutic agents. |
| Definition (PDQ) | A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39229&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39229&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C445" NCI Thesaurus) |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D004176 |
| SnomedCT | 387371005, 66859009 |
| English | Dipyramidole, Ethanol, 2,2',2'',2'''-((4,8-di-1-piperidinylpyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis-, 2,2',2'',2''''-[(4,8-Dipiperidinopyrimido-[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol, dipyridamole, DP, dipyridamole (medication), DIPYRIDAMOLE, Dipyridamole [Chemical/Ingredient], dipyramidole, Dipyridamole (product), Dipyridamole (substance), Dipyridamole |
| Swedish | Dipyridamol |
| Czech | dipyridamol |
| Finnish | Dipyridamoli |
| Russian | PERSANTIN, DIPIRIDAMOL, KURANTIL, ДИПИРИДАМОЛ, КУРАНТИЛ, ПЕРСАНТИН |
| Japanese | ジピリダモール |
| Italian | Dipiramidolo, Dipiridamolo |
| Polish | Dipirydamol |
| Spanish | dipiridamol (producto), dipiridamol (sustancia), dipiridamol, Dipiridamol |
| French | Dypyridamole |
| German | Dipyridamol |
| Portuguese | Dipiridamol |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Persantine (C0700020) |
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|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D004176 |
| English | Persantin, persantin, persantine, Persantine, Boehringer Ingelheim Brand of Dipyridamole |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Aggrenox (C0732282) |
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|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | C047634 |
| English | Aggrenox, aggrenox |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |