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Blood Transfusion
Aka: Blood Transfusion, pRBC, Packed Red Blood Cells
- See Also
- Transfusion Complication
- Transfusion Hemolysis
- Preparations
- Packed Red Blood Cells are derived from whole blood by removing 250 ml plasma
- Most centers filter Leukocytes before storage
- Decreases febrile nonhemolytic transfusion reaction risk
- CMV-safe
- Indications
- Acute Sickle Cell Crisis (CVA Prevention)
- Massive acute blood loss >1500 ml (30% of blood volume)
- Hemoglobin <7.0 g/dl and no serious comorbidity (and no ongoing bleeding)
- Hemoglobin <9.0 g/dl with serious comorbidity (e.g. cardiovascular disease, active bleeding)
- Symptomatic Anemia
- Severe Fatigue, weakness, or Dizziness
- Dyspnea
- Altered Level of Consciousness
- Angina
- Congestive Heart Failure
- Labs
- Hemoglobin
- Expect one unit pRBC to raise Hemoglobin by 1 g/dl
- Hematocrit
- Expect one unit pRBC to raise Hematocrit by 3%
- Adverse Effects
- See Transfusion Hemolysis (Immune Transfusion Reaction)
- See Transfusion Complication
- References
- Klein (2007) Lancet 370(9585): 415-26
- Sharma (2011) Am Fam Physician 83(6): 719-24