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Chemotherapy
Aka: Chemotherapy, Chemotherapy Extravasation
- General
- Exercise encouraged following high dose Chemotherapy
- Safe
- Prevents deconditioning
- Decreases toxic side effects of Chemotherapy
- Reference
- Dimeo (1997) Blood 90:3390-4
- Agents
- Alkylating Agent
- Antimetabolite Chemotherapy
- Hormonally Active Chemotherapy
- Plant Alkaloid Chemotherapy
- Antibiotic Chemotherapy
- Miscellaneous Medication
- Amsacrine
- Asparaginase
- Hydoxyurea
- Mitoxantrone
- Mitotane (Lysodren)
- Quinacrine
- Management: Extravasation of agents from IV
- Findings: Onset with hours of Chemotherapy
- Local erythema and swelling
- Necrosis
- Management
- Immediately stop any infusion
- Apply ice to area
- Do not compress area
- Use antidotes if available
- Urgent consultations with Oncology and Surgery
- Debridement may be needed
- Complications
- Scarring
- Contractures
- References
- Higdon (2006) Am Fam Physician 74:1873-80