Hematology and Oncology Book

http://www.fpnotebook.com/

White Blood Cell

Aka: White Blood Cell, WBC Count, Leukocyte, Leukopenia, Granulocyte
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  1. See Also
    1. Complete Blood Count
    2. Bone Marrow
  2. Physiology
    1. Granulocytes
      1. See Bone Marrow
      2. Granulocyte kinetics
        1. Cells in the Bone Marrow (90%)
          1. Proliferate and mature over 7 days
          2. Stored in the marrow up to 7 days
        2. Move to circulation with T1/2 of 6 hours (2%)
        3. Move into body tissues; die after 36 hours (8%)
    2. White Blood Cell Types
      1. Lymphocyte
      2. Monocyte
      3. Granulocytes
        1. Neutrophil
        2. Eosinophil
        3. Basophil
  3. Normal Range
    1. Age 6 Months to 2 years: 6.0 to 17.5 (Mean 11.0)
    2. Age 4 Years: 5.5 to 15.5 (Mean 9.1)
    3. Age 6 Years: 5.0 to 14.5 (Mean 8.5)
    4. Age 8 to 16 Years: 4.5 to 13.5 (Mean 8.1)
    5. Age over 21 Years: 4.5 to 11.0 (Mean 7.4)
  4. Increased White Blood Cell Count
    1. See Leukocytosis
  5. Decreased White Blood Cell Count (Leukopenia)
    1. Neutropenia (most common cause)
    2. Lymphocytopenia
    3. Monocytopenia
    4. Eosinopenia

granulocyte (C0018183)

Definition (NCI) A leucocyte with conspicuous cytoplasmic granules. In humans the granulocytes are also classified as polymorphonuclear leucocytes and are subdivided according to the staining properties of the granules into eosinophils, basophils and neutrophils. (On-line Medical Dictionary)
Definition (NCI) A type of immune cell that has granules (small particles) with enzymes that are released during infections, allergic reactions, and asthma. Neutrophils, eosinophils, and basophils are granulocytes. A granulocyte is a type of white blood cell.
Definition (MSH) Leukocytes with abundant granules in the cytoplasm. They are divided into three groups according to the staining properties of the granules: neutrophilic, eosinophilic, and basophilic. Mature granulocytes are the NEUTROPHILS; EOSINOPHILS; and BASOPHILS.
Definition (CSP) leukocytes with abundant neutrophilic, eosinophilic or basophilic granules in the cytoplasm; mature granulocytes are the neutrophils, eosinophils, and basophils.
Concepts Cell (T025)
MSH D006098
SnomedCT 256909001, 48791004
English Granulocytes, Granulocytic cell, NOS, granulocytes, Blood granulocytic cell, Granulocytic, granular leukocyte, Granular leucocyte, Granular leukocyte, cells granulocyte, Granulocyte, Granulocyte (cell), Granulocytic cell (cell), Granulocytic cell, Granulocyte (body structure), Granulocytic cell (body structure), granulocyte
French Polynucléaires, Polynucléaire, Granulocytes, Granulocyte
Swedish Granulocyter
Czech granulocyty
Finnish Granulosyytit
Russian GRANULOTSITY, LEIKOTSITY ZERNISTYE, ГРАНУЛОЦИТЫ, ЛЕЙКОЦИТЫ ЗЕРНИСТЫЕ
Croatian GRANULOCITI
Latvian Granulocīti
Polish Krwinki białe ziarniste, Granulocyty
Spanish célula granulocítica (célula), célula granulocítica (estructura corporal), célula granulocítica, granulocito (célula), granulocito, Granulocitos
German Granulozyten
Italian Granulociti
Dutch Granulocyt, Granulocyten
Portuguese Granulócitos
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Leukopenia (C0023530)

Definition (NCI) A laboratory test result indicating a decreased number of white blood cells in the peripheral blood.
Definition (NCI) A finding based on laboratory test results that indicate an decrease in number of white blood cells in a blood specimen.
Definition (CHV) an abnormally low white blood cell count
Definition (CHV) an abnormally low white blood cell count
Definition (CHV) an abnormally low white blood cell count
Definition (NCI) A condition in which there is a lower-than-normal number of leukocytes (white blood cells) in the blood.
Definition (CSP) reduction in the number of leukocytes in the blood, the count being 5000 per cubic millimeter or less.
Concepts Disease or Syndrome (T047)
MSH D007970
ICD9 288.50
ICD10 D72.819
SnomedCT 191348003, 142917003, 84828003, 419188005
English Leukopenias, LEUCOPENIA, Leukocytopenia, Leukocytopenias, LEUKOPENIA, Leucopenia, NOS, Leukopenia, NOS, Leukocytopenia, unspecified, leukopenia (diagnosis), leukopenia, Leucopenia (disorder), Leucopenia (finding), Leucocytopenia, Leukocytopenia NOS, White blood cell decreased, Leukopenia [Disease/Finding], Leukopenia, leukocytopenia, leucopenia, Leukopenia NOS, Leucopenia, Leukopenia (disorder), Decreased blood leucocyte number, Decreased blood leukocyte number (finding), Decreased blood leukocyte number
French LEUCOPENIE, Leucopénie SAI, Leucopénie, Leucocytopénie
Portuguese LEUCOPENIA, Leucopenia NE, Leucocitopenia, Leucopenia
Spanish LEUCOPENIA, disminución del número de leucocitos, leucopenia (hallazgo), Leucopenia NEOM, Leukopenia, Leucopenia, leucopenia (trastorno), leucopenia, Leucocitopenia
German LEUKOPENIE, Leukopenie NNB, Leukopenie, Leukozytopenie
Dutch leukopenie NAO, leukocytopenie, leukopenie, Leukocytopenie, Leukopenie
Italian Leucopenia NAS, Leucocitopenia, Riduzione dei leucociti, Leucopenia
Japanese 白血球減少症ＮＯＳ, ﾊｯｹｯｷｭｳｹﾞﾝｼｮｳｼｮｳ, ﾊｯｹｯｷｭｳｹﾞﾝｼｮｳｼｮｳNOS, 白血球減少, 白血球減少症
Swedish Leukopeni
Czech leukopenie, Leukocytopenie, Leukopenie, Leukopenie NOS
Finnish Leukosytopenia
Russian LEIKOPENIIA, ЛЕЙКОПЕНИЯ
Croatian LEUKOCITOPENIJA, LEUKOPENIJA
Polish Leukopenia
Hungarian Leukocytopenia, Leucopenia, leukopenia k.m.n., Leucocytopenia, leukopenia
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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