II. Indication

  1. Highly specific for Systemic Lupus Erythematosus

III. Causes: Negative

  1. Normal

IV. Causes: Positive (percentage refers to Test Sensitivity)

  1. Systemic Lupus Erythematosus
    1. Test Sensitivity: 39.7%
    2. Test Specificity: 98.6%
  2. Associated with Lupus Nephritis
  3. Drug Induced Lupus (<5%)

V. References

  1. Gladman in Klippel (1997) Rheumatic Diseases p. 255-6
  2. Peng in Ruddy (2001) Kelley's Rheumatology, p. 161-72
  3. Ali (2018) Am Fam Physician 98(3): 164-70 [PubMed]
  4. Callegari (1995) Postgrad Med, 97(4):65-74 [PubMed]
  5. Lane (2002) Am Fam Physician 65(6):1073-80 [PubMed]

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Related Studies

Ontology: Sm antibody (C0587072)

Concepts Amino Acid, Peptide, or Protein (T116) , Immunologic Factor (T129)
SnomedCT 46195008, 259926006, 309559007, 41560000
English Smith antibody, Anti Smith antibody, Sm - Smith antibody, anti-sm antibody, smith antibody, anti smith antibody, antibodies sm, antibodies smith, anti sm antibodies, sm antibody, Smith antibody (substance), Sm antibody (substance), Anti SM antibody (substance), Anti SM antibody, Anti-Sm Antibody, Sm antibody, Blood group antibody Smith, Blood group antibody Smith (substance), Anti SM antibody (substance) [Ambiguous]
Spanish anticuerpo Smith - Sm, anticuerpo anti Smith, anticuerpo anti SM, anticuerpo sm, anticuerpo de Smith (sustancia), anticuerpo de Smith, anticuerpo sm (sustancia), anticuerpo anti SM (sustancia), anticuerpo anti SM (concepto no activo), anticuerpo de grupo sanguĂ­neo Smith (sustancia), anticuerpo de grupo sanguĂ­neo Smith