II. Causes: Medications Causing Hyperkalemia
- Drugs that increase Potassium release from cells
- Digoxin (esp. digoxin Poisoning)
- Succinylcholine
- Aminocaproic acid
- Cyclosporine
- Tacrolimus
- Altered transmembrane Potassium shift
- Drugs that decrease renal Potassium excretion
- Potassium sparing Diuretics
- Potassium-Sparing Diuretic and Aldosterone Antagonists
- Agents that reduce Aldosterone secretion
- ACE Inhibitors
- Angiotensin Receptor Blockers (ARB)
- Yasmin (Spironolactone-like effect)
- NSAIDs
- Trimethoprim
- Blocks collecting tubule Sodium channel
- Do not combine with ACE Inhibitors, Angiotensin Receptor Blockers, Spironolactone
- Higher risk with age >65 years, Renal Insufficiency, Diabetes Mellitus and Heart Failure
- Fralick (2014) BMJ 349:g6196 +PMID:25359996 [PubMed]
- Other decreased renal excretion
- Other agents
- Antifungals (Ketoconazole, Fluconazole, Itraconazole)
- Fluorosis
- Hypertonic Infusions (Mannitol, Glucose)
- Penicillin G (high dose)
- Transfusions of pRBC
III. Causes: Herbal supplements that may increase Potassium
IV. Causes: Excessive Potassium intake
- See Potassium Supplementation
- Salt Substitute (e.g. Mrs. DASH)
- Fruits (Bananas, melons, orange juice)
V. References
Images: Related links to external sites (from Bing)
Related Studies
| Concepts | Disease or Syndrome (T047) |
| SnomedCT | 237849008 |
| Spanish | hipercaliemia medicamentosa, hipercalemia farmacógena (trastorno), hipercaliemia medicamentosa (trastorno), hiperpotasemia medicamentosa, hipercalemia farmacógena |
| English | Drug-induced hyperkalaemia, Drug-induced hyperkalemia, Drug-induced hyperkalemia (disorder) |
