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Ontology:
Citalopram
(C0008845)
Definition (CHV)
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a kind of antidepressant drug
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Definition (CHV)
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a kind of antidepressant drug
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Definition (NCI)
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A bicyclic phthalene derivative and selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activities. Citalopram selectively inhibits the neuronal reuptake of the neurotransmitter serotonin (5-HT) in presynaptic cells in the central nervous system, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on its receptors. Increased serotonergic neurotransmission results in antidepressive and anxiolytic effects.
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Definition (MSH)
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A furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.
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Definition (CSP)
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selective neuronal serotonin reuptake inhibitor and a clinically effective antidepressant with tolerable side effects; effective in reducing ethanol uptake in alcoholics.
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Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
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MSH |
D015283
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SnomedCT |
321986007, 372596005 |
LNC |
LP20806-3, MTHU012380 |
English |
Citalopram, Cytalopram, 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, CITALOPRAM, Citalopram [Chemical/Ingredient], cytalopram, Nitalapram, 1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile, citalopram, Citalopram (product), Citalopram (substance) |
Swedish |
Citalopram
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Czech |
citalopram
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Finnish |
Sitalopraami
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Russian |
TSITALOPRAM, ЦИТАЛОПРАМ |
Japanese |
シタロプラム
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Polish |
Citalopram
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Spanish |
citalopram (producto), citalopram (sustancia), citalopram, Citalopram |
French |
Citalopram
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German |
Citalopram
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Italian |
Citalopram
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Portuguese |
Citalopram
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Ontology:
Celexa
(C0719199)
Definition (CHV)
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depression treatment drug
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Concepts |
Organic Chemical
(T109)
, Pharmacologic Substance
(T121)
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English |
Celexa, citalopram hydrobromide (Celexa), CeleXA |
Ontology:
Escitalopram
(C1099456)
Definition (NCI_NCI-GLOSS)
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A drug used to treat depression and certain anxiety disorders. It belongs to the family of drugs called selective serotonin reuptake inhibitors (SSRIs).
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Definition (NCI)
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The active S-stereoisomer of the selective serotonin reuptake inhibitor (SSRI) citalopram with antidepressant, anti-obsessive-compulsive and antibulimic properties. Escitalopram inhibits the reuptake of the neurotransmitter serotonin (5-HT) at the serotonin reuptake pump of the neuronal membrane of the presynaptic cell, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on 5HT1A autoreceptors. Unlike other SSRIs, escitalopram appears to not only bind to a primary high-affinity site on the serotonin transporter protein but also to a secondary lower-affinity allosteric site that is considered to stabilize and prolong drug binding.
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Definition (MSH)
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S-enantiomer of citalopram.
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Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
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MSH |
D015283
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SnomedCT |
395246009, 400447003 |
LNC |
LP31801-1, MTHU016070 |
French |
Escitalopram
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English |
S(+)-Citalopram, (S)-Citalopram, ESCITALOPRAM, escitalopram, Escitalopram (product), Escitalopram (substance), Escitalopram |
Japanese |
エスシタロプラム
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Czech |
escitalopram
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Spanish |
escitalopram (producto), escitalopram (sustancia), escitalopram |
Ontology:
Lexapro
(C1170371)
Definition (CHV)
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a drug used to treat depression and anxiety
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Definition (MSH)
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Trade name of escitalopram, the active S-enantiomer of the racemic citalopram.
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Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
MSH |
D015283
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English |
Lexapro
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Czech |
Lexapro
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