Pharm

Temazepam

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Temazepam, Restoril

  • See Also
  • Class
  1. Medium Acting Benzodiazepine
  • Indications
  1. Insomnia with frequent awakening
  • Dose
  1. Restoril 7.5 to 30 mg PO 1-2 hours before bedtime
  • Pharmacokinetics
  1. Onset: 30-60 minutes
  2. Duration: 6-8 hours
  3. Half-Life: 8-12 hours
  4. Serum levels peak in 2-3 hours after oral dose
  • Background
  1. Weekly Cost: $1-2
  2. Exception: 7.5 mg costs $200/month
  • Advantages
  1. Less daytime sedation or accumulation
  • Disadvantages
  1. More risk of rebound Insomnia
  • Equivalent dosing (for Benzodiazepine Withdrawal)
  1. Valium = Dose x1.0
  2. Phenobarbital = Dose x3.0