Pharm
Clonazepam
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Clonazepam
, Klonopin
See Also
Benzodiazepine
Class
Long acting
Benzodiazepine
Indications
Anxiety Disorder
Tic Disorder
or
Tourette's Syndrome
Seizure Disorder
Lennox-Gastaut Syndrome
Akinetic
Seizure
Myoclonic
Seizure
Dosing
Initial: 0.25 to 0.5 mg PO tid
Titrate: Increase by 0.5 to 1 mg increments q3 days
Maximum Daily Dose: 20 mg
Pharmacokinetics
Half Life: 24-48 hours
Rapidly and completely absorbed PO
Equivalent Dosing (for Benzodiazepine Withdrawal)
Valium
= Clonazepam Dose x2.5
Phenobarbital
= Clonazepam Dose x7.5
Adverse Effects
Sedation
Weight gain
Impaired academic performance
Social anxiety with
School Refusal
in children
Worsening of attention in children with
ADHD
Hypersalivation
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