Pharm

Clonazepam

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Clonazepam, Klonopin

  • See Also
  1. Benzodiazepine
  • Class
  1. Long acting Benzodiazepine
  • Indications
  1. Anxiety Disorder
  2. Tic Disorder or Tourette's Syndrome
  3. Seizure disorder
    1. Lennox-Gastaut Syndrome
    2. Akinetic Seizure
    3. Myoclonic Seizure
  • Dosing
  1. Initial: 0.25 to 0.5 mg PO tid
  2. Titrate: Increase by 0.5 to 1 mg increments q3 days
  3. Maximum Daily Dose: 20 mg
  • Pharmacokinetics
  1. Half Life: 24-48 hours
  2. Rapidly and completely absorbed PO
  • Equivalent Dosing (for Benzodiazepine Withdrawal)
  1. Valium = Clonazepam Dose x2.5
  2. Phenobarbital = Clonazepam Dose x7.5
  • Adverse Effects
  1. Sedation
  2. Weight gain
  3. Impaired academic performance
  4. Social anxiety with School Refusal in children
  5. Worsening of attention in children with ADHD
  6. Hypersalivation