Analgesic

Capsaicin

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Capsaicin, Zostrix

  • Mechanism
  1. Derived from jalapeno peppers
  2. Depletes Substance P from pain fibers
  3. Requires frequent and repeat applications for affect
  4. Inconsistent use not effective
  • Dose
  • Capsaicin Cream (OTC)
  1. Apply Capsaicin cream (0,025% to 0.075%) to affected area 3-5 times daily
  • Dose
  • Capsaicin Patch (high dose - 8%)
  1. Applied in office
  2. Pre-treat area by applying 4% Lidocaine cream for 60 minutes
  3. Check area for anesthesia following application
  4. Apply Capsaicin 8% cream with gloves and leave on for 60 minutes
  5. Wash off after 1 hour
  • Adverse effects
  1. Burning sensation on initial application
  2. Increased pain for up to first week of application
  • Precautions
  1. Wash hands thoroughly after Capsaicin application