Nonasthmatic Eosinophilic Bronchitis


Nonasthmatic Eosinophilic Bronchitis, Eosinophilic Bronchitis

  • See Also
  • Epidemiology
  1. Emerging cause of Chronic Cough in pulmonology clinics
  2. Responsible for 10-30% of Chronic Cough cases referred to pulmonology
  • Differential Diagnosis
  • Diagnosis
  1. Normal airway hyper-responsiveness (i.e. not Asthma)
    1. Normal Spirometry
    2. Normal airway responsiveness on methacholine inhalation test
  2. Sputum Eosinophilia (i.e. not Chronic Bronchitis)
    1. Induced Sputum (via saline nebulization) with 3% or more Eosinophils
  3. No signs variable airflow obstruction
  • Management
  1. Does not respond to Inhaled Bronchodilators
  2. Eliminate Occupational Lung Disease and inhaled allergan exposures
  3. High-dose Inhaled Corticosteroids
  4. Brief initial course of Systemic Corticosteroids may be considered if Inhaled Corticosteroids ineffective