Pharm

Chloroquine

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Chloroquine, Aralen

  1. Areas without Chloroquine resistance
  • Safety
  1. Safe in all trimesters of pregnancy
  2. Safe for children of all ages
  • Dose
  • Prophylaxis
  1. Protocol
    1. Start 1-2 weeks before travel
    2. Continue through 4 weeks after return
  2. Adult: 300 mg base (500 mg salt) PO once weekly
  3. Child: Dose: 5 mg/kg base (8.3 mg/kg salt) up to 300 mg base orally once weekly
  • Directions
  1. Taking with food decreases gastric irritation
  • Adverse Effects
  1. Blurred vision
  2. Tinnitus
  3. Hearing Loss
  • Efficacy
  1. Most world regions exhibit high Chloroquine resistance in Plasmodium Falciparum