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Vaccination in Pregnancy

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Vaccination in Pregnancy, Immunization in Pregnancy

  • Class C
  • Small risk in controlled animal studies
  1. Td (Tetanus Toxoid and Diphtheria Toxoid)
    1. Give Tdap at 27-36 weeks gestation in each pregnancy
    2. Allows time for maternal Pertussis antibodies to transfer to the baby
    3. (2013) Ann Intern Med 158(3):191-9 [PubMed]
  2. Hepatitis A Vaccine
    1. Give if travel to endemic area or IVDA in pregnancy
  3. Hepatitis B Vaccine
    1. Administer in pregnancy for Hepatitis B risk factor
  4. Influenza Vaccine
    1. Indicated if pregnant in Influenza season
    2. Immunize after first trimester
  5. Meningococcal Vaccine
    1. Standard indications (dormitory, barracks, travel)
  6. Plague Vaccine
  7. Polyvalent pneumococcal Vaccine
    1. Vaccinate high risk women before pregnancy
    2. ACIP recommends avoiding during pregnancy
  8. Polio Vaccine (live and inactivated)
    1. Avoid during pregnancy in most cases
    2. Use IPV in pregnancy if high risk Polio exposure
  9. Rabies Vaccine
  10. Tularemia Vaccine
  11. Typhoid Vaccine
  • Class D
  • Strong evidence of risk to the human fetus
  • Class X
  • Very high risk to the human fetus
  1. BCG vaccine (Bacille Calmette-Guerin Vaccine)
  2. Measles Vaccine
  3. Mumps Vaccine
  4. Rubella Vaccine
  5. Small Pox Vaccine
  6. TC-83 Venezuelan Equine EncephalitisVaccine
  7. Varicella Vaccine (Varivax)
    1. Risk if vaccinated within 4 weeks of conception
    2. Theoretic risk only; not an indication for EAB
  • Resources
  1. CDC Guidelines for vaccinating pregnant women
    1. http://www.cdc.gov/nip/publications/preg_guide.htm