Antibiotic Resistance


Antibiotic Resistance, Antibiotic Resistant Infection, Antimicrobial Resistance, Multidrug-Resistant Organism, Multi-Drug Resistant Bacteria

  • Epidemiology
  1. Health Care Associated Infections are caused by multidrug resistant organisms in 16% of cases (especially MRSA)
  • Pathophysiology
  • Factors Affecting Drug Resistance
  1. Antibiotic Overuse
    1. Viral Upper Respiratory Infections
    2. Agricultural antibiotic use
  2. Increasing Incidence of immunocompromised patients
  3. Food supply globalization
  • Prevention
  1. Antibiotic Stewardship
    1. Limit antibiotics to cases in which they are absolutely indicated
  2. Prevent spread
    1. See Health Care-Associated Infection
    2. Practice good Hand Hygiene before and after seeing each paint
    3. Follow contact precautions for colonized or infected patients
    4. Consider culturing for nasal MRSA in high risk hospital settings (e.g. ICU) and decolonization with Bactroban of infected patients
  3. Decolonization
    1. Chlorhexidine baths daily for Intensive Care unit patients
  • Resources
  1. Centers for Disease Control
    1. Patient Education Tools on appropriate antibiotic use
      1. http://www.cdc.gov/antibioticresistance/tools.htm
  2. Patient Education from FamilyDoctor.org
    1. Antibiotic Resistance
      1. http://www.familydoctor.org/handouts/659.html
    2. Antibiotic Indications
      1. http://www.familydoctor.org/handouts/680.html