Leukemia

Chronic Leukemia

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Chronic Leukemia

  • Epidemiology
  1. Chronic Leukemia is primarily an adult cancer
  • Symptoms
  1. Asymptomatic at presentation (incidentally diagnosed based on CBC with Leukocytosis)
    1. Chronic Lymphocytic Leukemia
      1. Asymptomatic at diagnosis: 50%
    2. Chronic Myelogenous Leukemia
      1. Asymptomatic at diagnosis: 20%
  2. Constitutional symptoms
    1. Much less common in Chronic Leukemia than with Acute Leukemia)
    2. Chronic Lymphocytic Leukemia: 15%
    3. Chronic Myelogenous Leukemia: 30%
  • Labs
  1. Complete Blood Count
    1. Leukocytosis >20,000/mm3 in most cases (often >100,000/mm3)
    2. Contrast with normal white cell counts or Leukopenia associated with Acute Leukemias