HemeOnc

Breast Cancer Diagnosis

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Breast Cancer Diagnosis, Ductal Carcinoma of the Breast, Lobular Carcinoma of the Breast

  • Technique
  • Tissue Sampling
  1. Fine Needle Aspiration (FNA)
  2. Core Needle Biopsy
  3. Biopsy with Needle Guidance (Image-Guided Biopsy)
  4. Biopsy of Palpable Mass
  5. Incisional Biopsy (Surgical Biopsy)
  6. Sentinel Lymph Node Biopsy
  1. Ductal Carcinoma Type (Most common)
    1. Ductal Carcinoma In Situ (DCIS)
      1. Basement membrane intact
    2. Invasive Ductal Carcinoma
      1. Broken through wall of duct
  2. Lobular Carcinoma
    1. Lobular Carcinoma In Situ (LCIS)
      1. Not considered a cancer and biopsied lesion will not progress
      2. High risk for future Breast Cancer
    2. Lobular neoplasia
  • Types
  • Biomarkers
  1. Estrogen Receptors
  2. Progesterone Receptors
  3. ERBB2 Gene (previously HER2)
  1. Grade 1: Well Differentiated
  2. Grade 2: Moderately Differentiated
  3. Grade 3: Poorly Differentiated