Lab

Alkaline Phosphatase

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Alkaline Phosphatase

  • Normal
  • 30-120 U/L
  • Increased
  1. Gastrointestinal Disease
    1. Bowel Disease
      1. Ulcerative Colitis
      2. Bowel perforation
    2. Hepatic Cholestasis
      1. Fatty Liver
      2. Alcoholic Hepatitis
      3. Benign or malignant liver tumor
      4. Primary biliary Cirrhosis
      5. Drug induced liver disease
      6. Hepatic granuloma
      7. Hepatic Cyst
    3. Biliary Cholestasis
      1. Cholecystitis
      2. Cholelithiasis
      3. Primary Sclerosing Cholangitis
      4. Primary biliary Cirrhosis
  2. Bone disease
    1. Paget's Disease
    2. Osteitis Deformans
    3. Rickets
    4. Osteomalacia
    5. Bone Cancer or bone metastases
    6. Healing Fracture
  3. Endocrine disease
    1. Hypervitaminosis D
    2. Hyperparathyroidism
    3. Hyperthyroidism
    4. Acromegaly
  4. Infectious disease
    1. Epstein Barr Virus (EBV)
    2. Cytomegalovirus (CMV)
    3. Sepsis
  5. Medications
    1. Estrogens
      1. Estrogen Replacement Therapy
      2. Oral Contraceptives
    2. Albumin
    3. Erythromycin (and other antibiotics)
    4. Phenothiazines
  6. Other Causes
    1. Pulmonary Infarction
    2. Congestive Heart Failure
    3. Leukemia
    4. Myelofibrosis
    5. Multiple Myeloma
  • Decreased
  1. Hypothyroidism
  2. Pernicious Anemia
  3. Hypophosphatemia
  4. Hypervitaminosis D
  5. Poor nutrition