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Auralgan

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Auralgan, Benzocaine with Antipyrine, U-polycosanol 410, Aurodex

  • Background
  1. In U.S., FDA forced manufacturers to stop producing Auralgan, Aurodex, A/B Otic...
    1. FDA cited that these agents were unapproved and without evidence of benefit or safety
    2. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm453348.htm
  • Indications
  • Adverse Effects
  • Benzocaine related (in Aurodex)
  • Precautions
  1. Risk of Methemoglobinemia
    1. Not recommended in age under 2 years
    2. Given lack of topical alternatives, age limit handicaps the Acute Otitis Media Observation protocol
  2. Avoid overuse and stop if topical reaction
    1. Benzocaine (in Aurodex) is a common cause of Contact Dermatitis
  3. Avoid "new" Auralgan containing U-polycosanol 410 (uproven benefit)
    1. Costs $150 instead of old generic version price of $2
    2. Write to allow pharmacist to substitute with Generic Drug (either Aurodex or Benzocaine with Antipyrine)
  • Dosing
  1. Use 2-4 drops three to four times daily
  • Reference
  1. (2014) Presc lett 21(6): 36
  2. (2008) Presc Lett 15(5): 26