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Eosinophilia Syndrome

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Eosinophilia Syndrome, Nares Syndrome, Nonallergic Rhinitis with Eosinophilia

  • Definitions
  1. Nonallergic Rhinitis with Eosinophilia
    1. Subtype of Chronic Nonallergic Rhinitis characterized by nasal Eosinophilia
  • Epidemiology
  1. Perennial Non-allergic Rhinitis
  2. More common in adults
    1. May represent up to a third of Rhinitis cases
  • Symptoms
  1. Congestion
  2. Rhinitis
  • Labs
  1. Allergy Testing (RAST or Skin Testing) negative
  2. Nasal secretion microscopy
    1. Nasal Eosinophilia and mast cell degranulation
  • Differential Diagnosis
  • Associated conditions
  • Triad
  1. Aspirin sensitivity
  2. Non-IgE-mediated Asthma
  3. Nasal Polyps