Lemierre Syndrome


Lemierre Syndrome, Fusobacterium Pharyngitis

  • Pathophysiology
  1. Infection by Fusobacterium necrophorium
    1. Responsible for 10% of acute Pharyngitis cases in young adults and adolescents
  2. Occurs with contiguous infection from Pharyngitis (typically) or Dental Infection to lateral pharyngeal space
  3. Results in septic Thrombophlebitis of internal Jugular Vein
  • Epidemiology
  1. Adolescents and young adults make up majority of cases
  • Complications
  1. High morbidity and mortality
  2. Metastatic infection
  3. Septic pulmonary emboli
  • Management
  • Consider empiric treatment
  • References
  1. Edson (2011) Internal Medicine, Mayo Conference, Kauai