Pharm

Metoprolol

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Metoprolol, Lopressor, Metoprolol Succinate, Metoprolol Tartrate, Toprol XL

  • See Also
  1. Beta Blocker
  • Mechanism
  1. Selective Beta Blocker
  • Indications
  1. Myocardial Infarction
  2. Atrial Fibrillation Rate Control
  • Pharmacokinetics
  1. Intravenous dosing
    1. Onset of action in 5 minutes after intravenous dose
    2. Sustained response for 6-8 hours
  • Dosing
  1. Oral: Metoprolol Succinate (Toprol XL, extended release)
    1. Preferred oral formulation
    2. Dose: 50-100 mg orally daily (Maximum 400 mg/day)
  2. Oral: Metoprolol Tartrate (Lopressor, immediate release)
    1. Dose: 50 mg orally twice daily (Maximum 450 mg/day)
  3. Intravenous Metoprolol (Lopressor)
    1. Load: 2.5 to 5 mg IV over 2 to 5 minutes
    2. Repeated up to 3 doses (15 mg maximum)