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Metoprolol
Aka: Metoprolol, Lopressor, Metoprolol Succinate, Metoprolol Tartrate, Toprol XL- See Also
- Mechanism
- Selective Beta Blocker
- Indications
-
Pharmacokinetics
- Intravenous dosing
- Onset of action in 5 minutes after intravenous dose
- Sustained response for 6-8 hours
- Intravenous dosing
- Dosing
- Oral: Metoprolol Succinate (Toprol XL, extended release)
- Preferred oral formulation
- Dose: 50-100 mg orally daily (Maximum 400 mg/day)
- Oral: Metoprolol Tartrate (Lopressor, immediate release)
- Dose: 50 mg orally twice daily (Maximum 450 mg/day)
- Intravenous Metoprolol (Lopressor)
- Load: 2.5 to 5 mg IV over 2 to 5 minutes
- Repeated up to 3 doses (15 mg maximum)
- Oral: Metoprolol Succinate (Toprol XL, extended release)
| Medication Costs | ||
|---|---|---|
| Metoprolol Tartrate (on 6/18/2017 at Walmart.com) | ||
| Metoprolol Tartrate 100mg | #60 tablets for $4.00 | $0.07 each |
| Metoprolol Tartrate 100mg | #180 tablets for $10.00 | $0.06 each |
| Metoprolol Tartrate 25mg | #60 tablets for $4.00 | $0.07 each |
| Metoprolol Tartrate 25mg | #180 tablets for $10.00 | $0.06 each |
| Metoprolol Tartrate 50mg | #60 tablets for $4.00 | $0.07 each |
| Metoprolol Tartrate 50mg | #180 tablets for $10.00 | $0.06 each |
| metoprolol (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing) | ||
| METOPROLOL SUCC ER 100 MG TAB | Generic | $0.39 each |
| METOPROLOL SUCC ER 200 MG TAB | Generic | $0.75 each |
| METOPROLOL SUCC ER 25 MG TAB | Generic | $0.22 each |
| METOPROLOL SUCC ER 50 MG TAB | Generic | $0.23 each |
| METOPROLOL TARTRATE 100 MG TAB | Generic | $0.04 each |
| METOPROLOL TARTRATE 25 MG TAB | Generic | $0.02 each |
| METOPROLOL TARTRATE 50 MG TAB | Generic | $0.02 each |
| METOPROLOL-HYDROCHLOROTHIAZIDE 100-25 MG TAB | Generic | $1.04 each |
| METOPROLOL-HYDROCHLOROTHIAZIDE 50-25 MG TAB | Generic | $0.81 each |
| toprol xl (on 1/18/2017 at Medicaid.Gov Pharmacy Drug pricing) | ||
| TOPROL XL 100 MG TABLET | Generic | $0.39 each |
| TOPROL XL 25 MG TABLET | Generic | $0.22 each |
| TOPROL XL 50 MG TABLET | Generic | $0.23 each |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
Metoprolol (C0025859) |
|
|---|---|
| Definition (MSH) | A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS. |
| Definition (NCI) | A cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction leading to a reduction in cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thereby preventing vasoconstriction and aldosterone secretion. |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D008790 |
| SnomedCT | 372826007, 7092007 |
| LNC | LP16204-7, MTHU016612 |
| English | Metoprolol, 2-Propanol, 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)-, (+-)-, metoprolol (medication), Metoprolol [Chemical/Ingredient], METOPROLOL, metoprolol, Metoprolol (product), Metoprolol (substance) |
| Swedish | Metoprolol |
| Czech | metoprolol |
| Finnish | Metoprololi |
| Russian | N 93-26, METOPROLOL, МЕТОПРОЛОЛ, Н 93-26 |
| Japanese | 酒石酸メトプロロール, セレクナート, メデピン, メルコモン, ロプレソール, セロケン, ロプレソールSR, シオプトロール, セグミューラー, ココナリン, シプセロン, モジュメニー, セロケンL, メトプリック, メトラスター, カルスホン, メトプロロール |
| Polish | Metoprolol |
| Spanish | metoprolol (producto), metoprolol (sustancia), metoprolol, Metoprolol |
| French | Métoprolol |
| German | Metoprolol |
| Italian | Metoprololo |
| Portuguese | Metoprolol |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Metoprolol Tartrate (C0700548) |
|
|---|---|
| Definition (NCI) | The tartrate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol tartrate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion. |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D008790 |
| SnomedCT | 318463000, 72770009 |
| English | Tartrate, Metoprolol, metoprolol tartrate, metoprolol tartrate (medication), METOPROLOL TARTRATE, Metoprolol Tartrate [Chemical/Ingredient], Metoprolol tartrate, Metoprolol tartrate (substance), Metoprolol tartrate [dup] (substance), Metoprolol Tartrate |
| French | Tartrate de métoprolol, Métoprolol tartrate |
| Spanish | tartrato de metoprolol (sustancia), tartrato de metoprolol |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Lopressor (C0700776) |
|
|---|---|
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D008790 |
| English | Lopresor, Novartis Brand of Metprolol Tartrate, lopresor, lopressor, Lopressor |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Toprol-XL (C0723783) |
|
|---|---|
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | C402833 |
| English | Toprol-XL, toprol-xl, toprol xl, Toprol XL |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
metoprolol succinate (C0724633) |
|
|---|---|
| Definition (NCI) | The succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol succinate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion. |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | C402833 |
| SnomedCT | 412432007 |
| English | metoprolol succinate (medication), metoprolol succinate, METOPROLOL SUCCINATE, metoprolol succinate [Chemical/Ingredient], succinate metoprolol, metoprolol CR-XL, Metoprolol succinate (substance), Metoprolol succinate, Metoprolol Succinate |
| Spanish | succinato de metoprolol (sustancia), succinato de metoprolol |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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