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Osteomalacia
Aka: Osteomalacia
- See Also
- Rickets (defective bone calcification in children)
- Definition
- Defective calcification of bone matrix in adults
- Pathophysiology
- Defective bone calcification after Growth Plates close
- Associated with increased Osteoblast activity
- Causes
- Vitamin D Deficiency
- Renal Tubular Acidosis (Vitamin D-Resistant)
- Symptoms
- Anorexia and weight loss
- Muscle Weakness
- Bone pain
- Signs
- Skull, spine and Pelvis with deformities
- See Vitain D Deficiency
- Radiology
- Pseudofractures (Looser's Zones)
- Radiolucent defects of skull, spine and Pelvis
- Transverse lines in bony cortex
- Vertebral Fractures
- Management
- See Vitamin D Deficiency
- References
- Drezner in Goldman (2004) Cecil Medicine, p. 1555-62
- Lane in Harris (2005) Kelly's Rheumatology, p. 1485-7