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Nephrogenic Diabetes Insipidus
Aka: Nephrogenic Diabetes Insipidus, Nephrogenic DI- See Also
- Pathophysiology
- Deficient response by Kidney to Antidiuretic Hormone (ADH)
- Contrast with Central Diabetes Insipidus (deficient ADH)
- ADH fails increasing collecting duct water permeability
- Failed countercurrent mechanism
- Inadequate generation of hypertonic interstitium
- Deficient response by Kidney to Antidiuretic Hormone (ADH)
- Causes
- Congenital
- Chronic disease of renal Medulla
- Medullary cystic disease
- Pyelonephritis
- Protein deficient diet
- Salt deficient diet
- Hypercalcemia
- Hypokalemia
- Amyloidosis
- Multiple Myeloma
- Medications
- Diagnosis
- Fluid Deprivation Test
- No response to water deprivation
- No response to exogenous ADH administration
- Hare-Hickey Test
- Increased ADH to Serum Osmolality ratio
- Fluid Deprivation Test
Nephrogenic Diabetes Insipidus (C0162283) |
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Definition (MSH) | A genetic or acquired polyuric disorder characterized by persistent hypotonic urine and HYPOKALEMIA. This condition is due to renal tubular insensitivity to VASOPRESSIN and failure to reduce urine volume. It may be the result of mutations of genes encoding VASOPRESSIN RECEPTORS or AQUAPORIN-2; KIDNEY DISEASES; adverse drug effects; or complications from PREGNANCY. |
Definition (NCI) | Diabetes insipidus caused by insensitivity of the kidneys to antidiuretic hormone. |
Definition (CSP) | polyuric disorder characterized by normal rates of renal filtration and solute excretion, but a persistent hypotonic urine due to the failure of renal tubules to respond to antidiuretic hormones, such as vasopressin, to reduce urine volume; tubular insensitivity to vasopressin can result from genetic defects, diseases, drug effects, or may occur with pregnancy. |
Concepts | Disease or Syndrome (T047) |
MSH | D018500 |
ICD9 | 588.1 |
ICD10 | N25.1 |
SnomedCT | 123294004, 111395007 |
English | DIABETES INSIPIDUS NEPHROGENIC, Diabetes Insipidus, Nephrogenic, NDI - Nephrogen diab insipidus, nephrogenic diabetes insipidus (diagnosis), nephrogenic diabetes insipidus, Diabetes insipidus nephrogenic, Nephrogenic diabetes insipidus, NOS, Nephrogenic Diabetes Insipidus, Nephrogen diabetes insip, Diabetes Insipidus, Nephrogenic [Disease/Finding], diabetes insipidus nephrogenic, diabete insipidus nephrogenic, Nephrogenic diabetes insipidus, NDI - Nephrogenic diabetes insipidus, Nephrogenic diabetes insipidus (disorder), diabetes; insipidus, nephrogenic, nephrogenic; diabetes insipidus, Nephrogenic diabetes insipidus -RETIRED- |
Spanish | DIABETES INSIPIDA NEFROGENICA, Diabetes insípida nefrógena, diabetes insípida nefrógena, diabetes insípida nefrogénica, diabetes insípida nefrogénica - RETIRADO - (concepto no activo), diabetes insípida nefrogénica - RETIRADO -, diabetes insípida nefrógena (trastorno), Diabetes insípida nefrogénica, Diabetes Insípida Nefrogénica |
Dutch | diabetes insipidus nefrogeen, diabetes; insipidus, nefrogeen, nefrogeen; diabetes insipidus, nefrogene diabetes insipidus, Diabetes insipidus, nefrogene, Nefrogene diabetes insipidus |
French | Diabète insipide néphrogène, DIABETE INSIPIDE NEPHROGENIGUE, DIN (Diabète Insipide Néphrogénique), Diabète insipide néphrogénique |
German | Diabetes insipidus nephrogen, DIABETES INSIPIDUS NEPHROGEN, Renaler Diabetes insipidus, nephrogener Diabetes insipidus, Diabetes insipidus, nephrogener |
Swedish | Diabetes insipidus, nefrogen |
Japanese | ジンセイニョウホウショウ, 腎形成性尿崩症, 尿崩症-腎性, 腎原発性尿崩症, 腎性尿崩症, 尿崩症-腎原発性 |
Czech | diabetes insipidus nefrogenní, Nefrogenní diabetes insipidus |
Finnish | Renaalinen diabetes insipidus |
Russian | DIABET NESAKHARNYI NEFROGENNYI, ДИАБЕТ НЕСАХАРНЫЙ НЕФРОГЕННЫЙ |
Portuguese | DIABETES INSIPIDUS NEFROGENICO, Diabetes insípida nefrogénica, Diabetes Insípido Nefrogênico |
Korean | 콩팥(신장성) 요붕증 |
Croatian | DIJABETES INSIPIDUS, NEFROGENI |
Polish | Moczówka prosta nerkowa |
Hungarian | nephrogen diabetes insipidus |
Norwegian | Nefrogen diabetes insipidus, Diabetes insipidus, nefrogen |
Italian | Diabete insipido nefrogeno |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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