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Idiopathic Cyclic Edema
Aka: Idiopathic Cyclic Edema, Idiopathic Edema
- Associated Conditions
- Premenstrual Syndrome
- Epidemiology
- Affects young women most commonly
- Pathophysiology
- No underlying systemic cause
- Related factors
- Increased capillary permeability
- Renin-Angiotensin-Aldosterone activation
- Associated conditions
- Obesity
- Diabetes Mellitus
- Hypothyroidism
- Signs
- No association with Menstrual Cycle
- Orthostatic Edema
- Water retention while upright
- Diuresis while supine
- Body weight increases >2 kg with edema
- Differential Diagnosis: Estrogen stimulated edema
- Increased Estrogen with Sodium and water retention
- Cyclic edema related to Menses
- Weight gain on edematous days: 1.5 to 2.5 kg
- Lower extremity Pitting Edema
- Diuresis follows Menses
- Orthostasis may occur with diuresis
- Management
- Avoid Diuretics (worsens edema)
- Restrict salt intake
- Consider ACE Inhibitor
- References
- Brenner and Rector (2000) Kidney, Saunders, p. 845-6